Transcriptional profiling of three siderophore gene clusters identified in A. baumannii ATCC 17978. Transcriptional alteration of the three siderophore gene clusters to low iron conditions are shown, (A) siderophore gene cluster 1 (A1S_1647-1657), (B) siderophore cluster 2 (A1S_2562-2581) and (C) the acinetobactin gene cluster (A1S_2372-2392). The top arrows show predicted gene function; siderophore biosynthesis in purple, receptors and uptake mechanisms in light orange, efflux pumps in orange and genes of unknown function in white. The relative transcriptional differences between A. baumannii grown under iron replete and iron limiting conditions are depicted in the bottom set of arrows according to the green color scale bar, all values are in times-fold difference. Genes depicted in white were not differentially expressed and those in dark green were overexpressed more than 25-fold. No significant down-regulation was observed within the siderophore gene clusters. Putative FUR boxes are shown as black arrows.
Eijkelkamp et al. BMC Genomics 2011 12:126 doi:10.1186/1471-2164-12-126