Comparative genome structure of strains 95010 (Mmc), PG1 (MmmSC) and California kid (Mcc). The graph represents an alignment of the colinear blocks, identified by MAUVE, that are conserved in three closely related genomes: Mmc 95010; MmmSC PG1; Mcc California kid. Numbers 1 to 6 refer to large DNA fragments of the Mmc 95010 genome with apparently no homology in the other two genomes. Numbers 7 to 11 indicate DNA inversions (blocks below the central line) that distinguish Mmc from MmmSC. Comparison with the strain California kid genome allows identification of the genome in which these inversions have taken place. For blocks 7, 9, 10 and 11, the inversion took place in the MmmSC PG1 genome, whereas inversion 8 took place in the Mmc 95010 genome. The higher number of block rearrangements in the Mcc genome is in agreement with its taxonomic position and greater evolutionary distance from Mmc, as compared with MmmSC.
Thiaucourt et al. BMC Genomics 2011 12:114 doi:10.1186/1471-2164-12-114