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Meta-analysis of muscle transcriptome data using the MADMuscle database reveals biologically relevant gene patterns

Daniel Baron123*, Emeric Dubois123, Audrey Bihouée123, Raluca Teusan123, Marja Steenman123, Philippe Jourdon123, Armelle Magot345, Yann Péréon345, Reiner Veitia67, Frédérique Savagner1089, Gérard Ramstein11 and Rémi Houlgatte123

Author Affiliations

1 INSERM, U915, Nantes, F-44000 France

2 Université de Nantes, Faculté de Médecine, Nantes, F-44000, France

3 CHU de Nantes, l'Institut du Thorax, CIC, Nantes, F-44000, France

4 CHU de Nantes, Laboratoire d'Explorations Fonctionnelles, Nantes, F-44000, France

5 CHU de Nantes, Centre de Référence des Maladies Neuromusculaires Rares de l'Enfant et de l'Adulte Nantes-Angers, Nantes, F-44000, France

6 Institut Jacques Monod, UMR7592-CNRS, Paris, F-75013, France

7 Université Paris Diderot-Paris 7, Paris, F-75013, France

8 INSERM, UMR 694, Angers, F-49033, France

9 Université d'Angers, Angers, F-49033, France

10 CHU Angers, Laboratoire de Biochimie et Biologie moléculaire, Angers, F-49033, France

11 Laboratoire d'Informatique de Nantes Atlantique LINA, Ecole Polytechnique, Nantes, F-44000, France

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BMC Genomics 2011, 12:113  doi:10.1186/1471-2164-12-113

Published: 16 February 2011

Additional files

Additional File 1:

The MADMuscle web interface - database. In this supplementary file, we present the database web interface with different screenshots.

Format: DOC Size: 3.3MB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional File 2:

The MADMuscle web interface - meta-analysis tool. In this supplementary file, we present the meta-analysis tool web interface with different screenshots.

Format: DOC Size: 838KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional File 3:

Supplementary material and results. In this supplementary file, we give additional information and comments about the procedures and the results.

Format: DOC Size: 244KB Download file

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Open Data

Additional File 4:

Re- normalization of MADMuscle data sets. In this supplementary file, we illustrate the re-normalization procedure of each data set to correct remaining bias.

Format: DOC Size: 158KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data