Table 1

Comparison of ADHOC to Competing Clustering Methods for DIP Yeast PPI Dataset

Method

Cluster Number

Cluster Size

Discard (%)

GO (-log P-value)


MF

BP

CC


ADHOC

50

20.56

68.05

5.18

7.44

6.38

Maximal Clique

376

4.55

80.06

3.43

4.02

2.67

IPCA

253

4.64

80.39

3.61

4.09

2.89

DPClus

90

5.27

84.49

3.91

4.50

3.44

MCODE

29

23.76

75.21

4.20

5.23

4.89

CFinder

84

7.46

80.06

4.63

6.03

4.66


Cluster Number: the number of clusters identified by each method; Cluster Size: the average number of proteins in each cluster; Discard (%): the percentage of proteins not assigned to any cluster; GO: the average -log p-values (adjusted) of all detected clusters for Gene Ontology (molecular functions (MF), biological process (BP), and cellular component (CC)).

Liu et al. BMC Genomics 2010 11(Suppl 4):S17   doi:10.1186/1471-2164-11-S4-S17

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