Table 1

The essential differences of DAPID, 3D-partner and 3D-interologs

Feature/Methods

DAPID [23]

3D-partner [13]

3D-interologs


Homolog families of 3D- dimer template

NO

YES (BLASTP E-value <10-2)

YES (BLASTP E-value ≤10-10)

Scoring function:

Template interface score

NO

NO

YES (Esηm)

Top ranked strategy

NO

NO

YES (Top ranked N for each species)

Interface binding affinity

NO

YES (four matrices)

YES (four matrices)

Residue conservation score

NO

YES (PSSM)

YES (PSSM)

Score of aligned contact

residues

YES (BLOSUM62)

YES (BLOSUM62)

YES (BLOSUM62)

Service type

A database of domain-annotated protein interactions

A web tool predicts interacting partners and binding models of a query protein sequence

An evolution database of physical protein-protein interactions across multiple genomes


Lo et al. BMC Genomics 2010 11(Suppl 3):S7   doi:10.1186/1471-2164-11-S3-S7

Open Data