Figure 5.

Evaluation of the 3D-interologs in binding affinities. The Pearson correlations between experimental free energies (ddG) and the predicted values of the 3D-interologs using four scoring functions, including 3D-interologs (red), 3D-partner (blue), Esim (only template similarity, green) and one matrix (black) proposed by Lu, et al., on 275 mutated residues selected from Alanine Scanning Energetics database.

Lo et al. BMC Genomics 2010 11(Suppl 3):S7   doi:10.1186/1471-2164-11-S3-S7