Table 1

Functional annotations of the residues in rat imidase selected by FAVAT

FAVAT score ranking

FAVAT selected residues

Corresponding residues in 1GKQ1

Corresponding residues in 1KCX1

MSA predicted residues2

Functional annotation base on 1GKQ


1

His248

His239

Lys254

His239

Metal coordinate

2

His69

His61

Tyr75

His61

Metal coordinate

3

Arg302

Arg292

Ser308

Conformation

4

Lys159

Lys150 (Kcx)

Gln165

Metal coordinate

5

Met297

Met287

Thr303

Conformation

6

His67

His59

Asn73

His59

Metal coordinate

7

Asp326

Asp315

Gly332

Metal coordinate

8

Ala134

Ala126

Asp139

Secondary structure core residue

9

Ala34

Arg30

Gln44

Quaternary structure

10

His459

Trp448

Met465

Quaternary structure


1GKQ and 1KCX are the structure IDs of D-hydantoinase and collapsin response mediator proteins (CRMPs), respectively.

2MSA result according to the manuscript [66].

Hung et al. BMC Genomics 2010 11(Suppl 3):S14   doi:10.1186/1471-2164-11-S3-S14

Open Data