Comparison of ROC curves of DEG algorithms with/out DB pruning. It shows that WAD and t-Test have higher AUC values than FC and RP. Using DB pruning, tTest’s AUC value can be improved to be close to that of WAD. Actually, DB pruning significantly improves all DEG algorithms.
Hu and Xu BMC Genomics 2010 11(Suppl 2):S3 doi:10.1186/1471-2164-11-S2-S3