This article is part of the supplement: International Workshop on Computational Systems Biology: Approaches to Analysis of Genome Complexity and Regulatory Gene Networks

Open Access Research

Bimodal gene expression patterns in breast cancer

Marina Bessarabova1, Eugene Kirillov1, Weiwei Shi2, Andrej Bugrim2, Yuri Nikolsky2* and Tatiana Nikolskaya1

  • * Corresponding author: Yuri Nikolsky yuri@genego.com

  • † Equal contributors

Author Affiliations

1 Russian Academy of Sciences, Vavilov Institute for General Genetics, ul. Gubkina, 3, Moscow, Russia

2 Genego, Inc., 500 Renaissance Drive, St. Joseph, MI 49085, USA

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BMC Genomics 2010, 11(Suppl 1):S8  doi:10.1186/1471-2164-11-S1-S8

Published: 10 February 2010

Additional files

Additional file 1:

The list of bimodal genes (866). Worksheet 1. Data pre-processing. Describes pre-processing workflow for each data set. Worksheet 2. Bimodal genes. Includes list of 866 bimodal genes (see Results).

Format: XLS Size: 266KB Download file

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Additional file 2:

Raw data graphs. Expression profiles for bimodal genes in 5 data sets before normalization. Graphs.

Format: PDF Size: 766KB Download file

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Additional file 3:

Raw data box plots. Expression profiles for bimodal genes in 5 data sets before normalization. Box Plots

Format: PDF Size: 99KB Download file

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Additional file 4:

Normalized data graphs. Expression profiles for bimodal genes in 5 data sets after normalization. Graphs

Format: PDF Size: 623KB Download file

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Additional file 5:

Normalized data box plots. Expression profiles for bimodal genes in 5 data sets after normalization. Box Plots

Format: PDF Size: 83KB Download file

This file can be viewed with: Adobe Acrobat Reader

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Additional file 6:

"Close neighbors" expression groups of bimodal genes splits patients into groups.

Format: XLS Size: 44KB Download file

This file can be viewed with: Microsoft Excel Viewer

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