Table 2 |
||||
|
True positive rate at mass tolerance of 0.04 Da. |
||||
|
Type of methylation |
True positive rate (%) |
No. of methylation sites correctly matched |
No. of methylation sites tested |
No. of peptides tested |
|
|
||||
|
a) Non-redundant known mono- and di-methylation |
||||
|
Monomethyl-K |
100 |
27 |
466 |
1,201 |
|
Dimethyl-K |
98 |
89 |
280 |
699 |
|
Monomethyl-R |
N.D.a |
N.D.a |
3 |
6 |
|
Dimeth-R |
76 |
28 |
137 |
495 |
|
b) Artificial mono- and di-methylation |
||||
|
Monomethyl-K |
78 |
217 |
11,377 |
30,782 |
|
Dimethyl-K |
89 |
3,673 |
11,377 |
30,691 |
|
Monomethyl-R |
90 |
453 |
6,941 |
18,728 |
|
Dimethyl-R |
90 |
2,140 |
6,902 |
18,594 |
|
|
||||
|
a: N.D. - not determined |
||||
|
Pang et al. BMC Genomics 2010 11:92 doi:10.1186/1471-2164-11-92 |
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