Table 2

True positive rate at mass tolerance of 0.04 Da.

Type of methylation

True positive rate (%)

No. of methylation sites correctly matched

No. of methylation sites tested

No. of peptides tested


a) Non-redundant known mono- and di-methylation

Monomethyl-K

100

27

466

1,201

Dimethyl-K

98

89

280

699

Monomethyl-R

N.D.a

N.D.a

3

6

Dimeth-R

76

28

137

495

b) Artificial mono- and di-methylation

Monomethyl-K

78

217

11,377

30,782

Dimethyl-K

89

3,673

11,377

30,691

Monomethyl-R

90

453

6,941

18,728

Dimethyl-R

90

2,140

6,902

18,594


a: N.D. - not determined

Pang et al. BMC Genomics 2010 11:92   doi:10.1186/1471-2164-11-92

Open Data