Table 3

Comparison of α levels when restricting the definition of a haplotype

Method

Parameters

Significance Threshold

Corresponding α level


Gabriel

D'U > 0.98

2.72 × 10-7

0.151

D'L > 0.70

D'U > 0.98

2.11 × 10-7

0.12

D'L > 0.85

4-Gamete

Cutoff = 1%

3.06 × 10-7

0.166

Cutoff = 0.5%

2.50 × 10-7

0.139

Solid spine

D' = 0.80

3.71 × 10-7

0.195

D' = 0.95

2.79 × 10-7

0.155


Significance thresholds with corresponding α levels are given for each haplotype calling method with the standard parameters and a set of more restricted parameters. D'U and D'L represent the, upper and lower confidence limits of D', respectively.

Johnson et al. BMC Genomics 2010 11:724   doi:10.1186/1471-2164-11-724

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