Table 2

Cardiac enriched miRNAs

miRNA transcript

Location

EM-s

HT-s

Fold Difference


miRNA|ENSGALT00000028994|5p~|gga-mir-133a-1|sense #

chr2:105670407-105670428|-

0 ± 0

9 ± 1.3

inf

miRNA|ENSGALT00000028999|3p|gga-mir-1a-1|sense

chr20:8107876-8107896|-

0 ± 0

23 ± 6.9

inf

miRNA|ENSGALT00000029007|5p~|gga-mir-133c|sense #

chr23:4664062-4664083|+

0 ± 0

8 ± 2.9

inf

miRNA|ENSGALT00000035316|5p|gga-mir-499|sense #

chr20:2599386-2599408|-

2.8 ± 1.3

2542.5 ± 574

906

miRNA|ENSGALT00000035316|3p~|gga-mir-499|sense #

chr20:2599348-2599370|-

15.5 ± 1.1

3048.4 ± 318.2

196

miRNA|ENSGALT00000029007|3p|gga-mir-133c|sense #

chr23:4664099-4664120|+

2.8 ± 1.3

496.9 ± 44.9

177

miRNA|ENSGALT00000029006|5p~|gga-mir-1b|sense

chr23:4663916-4663936|+

1.7 ± 1.1

142.9 ± 22.7

83

miRNA|ENSGALT00000028999|5p~|gga-mir-1a-1|sense

chr20:8107838-8107858|+

35.4 ± 20.4

2366.1 ± 777.2

67

miRNA|ENSGALT00000029006|3p|gga-mir-1b|sense

chr23:4663953-4663973|+

91.1 ± 24.2

6086.5 ± 1328.3

67

miRNA|ENSGALT00000042439|5p||sense

chr4:2151195-2151215|+

1.4 ± 2

32.5 ± 0.4

23

miRNA|ENSGALT00000042439|3p||sense #

chr4:2151238-2151260|+

30.2 ± 6.1

1277.3 ± 123.2

42

miRNA|ENSGALT00000035276|3p|gga-mir-490|sense

chr1:59948716-59948737|-

45.3 ± 12.6

1447.5 ± 231.3

32

miRNA|ENSGALT00000042468|5p|gga-mir-1773|sense

chr20:8109147-8109169|+

1.1 ± 0.2

25.5 ± 3.8

23

miRNA|ENSGALT00000042438|3p|gga-mir-1799|sense

chr5:42365992-42366012|+

8.6 ± 6.9

130.5 ± 0.5

15

miRNA|ENSGALT00000035276|5p~|gga-mir-490|sense

chr1:59948755-59948776|-

13.8 ± 2.1

228.3 ± 47.4

17

miRNA|ENSGALT00000042432|3p~|sense

chr1:104486649-104486675|-

8.2 ± 4.6

84.6 ± 5.7

10

miRNA|ENSGALT00000029028|3p|gga-mir-133b|sense #

chr3:110384948-110384968|-

93 ± 21.6

866.5 ± 52.1

9.3

miRNA|ENSGALT00000042246|3p~|gga-mir-1731|sense

chr12:10938277-10938299|-

1.7 ± 1.1

15 ± 1.6

8.8

miRNA|ENSGALT00000042411|5p|gga-mir-1434|sense

chr28:1055205-1055224|+

26.5 ± 11.3

204.5 ± 18.6

7.7

miRNA|ENSGALT00000035271|3p|gga-mir-193b|sense

chr14:759503-759526|+

31.8 ± 0.3

213.2 ± 26

6.7

miRNA|ENSGALT00000042289|5p|gga-mir-1747|sense

chr2:62758752-62758773|-

2.1 ± 1.2

12.5 ± 0.6

6.1

miRNA|ENSGALT00000028974|5p|gga-mir-146a|sense

chr13:7555655-7555676|-

10.6 ± 4.2

60.6 ± 8.3

5.7

miRNA|ENSGALT00000028997|5p|gga-mir-30d|sense #

chr2:148337300-148337321|-

1452 ± 39.6

7275.3 ± 46.5

5.0

miRNA|ENSGALT00000042432|5p||sense

chr1:104486710-104486736|-

915.9 ± 102.7

3702.3 ± 152.3

4.0

miRNA|ENSGALT00000028990|3p~|gga-mir-138-1|sense

chr2:40745167-40745183|-

9.4 ± 2.4

33.5 ± 1

3.6

miRNA|ENSGALT00000028998|5p|gga-mir-30b|sense

chr2:148331648-148331669|-

461.2 ± 63

1638.4 ± 129.7

3.6

miRNA|ENSGALT00000029030|3p|gga-mir-223|sense

chr4:233007-233027|+

2759.8 ± 88

9608.1 ± 564.1

3.5

miRNA|ENSGALT00000042472|5p|gga-mir-1677|sense #

chr3:76659772-76659792|+

219.8 ± 31.9

725.3 ± 80.2

3.3

miRNA|ENSGALT00000028951|5p|gga-mir-125b|sense #

chr1:102457663-102457684|+

5255.7 ± 209.1

15151.5 ± 1241

2.9

miRNA|ENSGALT00000035272|3p|gga-mir-181a-1|sense

chr8:2001620-2001641|+

154.6 ± 49.6

424.6 ± 8.1

2.7

miRNA|ENSGALT00000029026|5p|gga-mir-30a|sense #

chr3:85102244-85102265|+

898.4 ± 20.4

2238.4 ± 52.7

2.5

miRNA|ENSGALT00000035333|3p|gga-mir-144|sense

chr19:5824134-5824155|-

79.4 ± 4.2

187.5 ± 8.9

2.4

miRNA|ENSGALT00000029015|5p|gga-let-7k|sense

chr26:1442955-1442976|-

11.8 ± 1

25.5 ± 3.8

2.2

miRNA|ENSGALT00000028983|5p|gga-mir-126|sense #

chr17:8431792-8431812|-

1310.7 ± 123.6

2561 ± 161.5

2.0

miRNA|ENSGALT00000029008|5p|gga-mir-30e|sense

chr23:5248432-5248450|+

1382.7 _ 30.5

2630.2 ± 3.1

1.9

miRNA|ENSGALT00000042329|3p~|gga-mir-1811|sense

chr4:58651749-58651768|+

60.9 _ 6

105.5 ± 4

1.7

miRNA|ENSGALT00000028959|3p~|gga-mir-18a|sense

chr1:152248637-152248658|-

49.1 _ 0.3

82.5 ± 2.8

1.7


Table of significantly cardiac enriched miRNA transcripts. Indicated are transcript name (EnsemblTranscript | 5p/3p | miRNA name | (anti)sense), genomic location, average expression values ± SD and the fold difference between samples. The ' ~' indicates miRNA transcripts for which the genomic positions were not present in the Ensembl database and thus were inferred from the complementary position of the hairpin structure. # indicates the difference in expression level was confirmed by qPCR.

Buermans et al. BMC Genomics 2010 11:716   doi:10.1186/1471-2164-11-716

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