Table 6

Real-time quantitative RT-PCR for selected genes in B6 and TH mice (males, 16 week, n = 5 each group).

Gene symbol

Gene name

Chr

Near marker

Trait

Tissue

Fold

P


1700009P17Rik

RIKEN cDNA 1700009P17 gene

1

D1Mit113

Tg

Chol

Liver

0.2

0.0007

Ccdc46

Coiled-coil domain containing 46

11

D11Mit132

Tg

Liver

7

0.0019

Sirpb1a

Signal-regulatory protein beta 1A

3

D3Mit304

Chol

Adipose tissue

2.6

0.02

Ctrc

Chymotrypsin C (caldecrin)

4

D4Mit312

Glu

Pancreas

17

<0.0001

Igfbp2

Insulin-like growth factor binding protein 2

1

D1Mit215

FPW

Liver

0.50

0.05

Adipose tissue

0.1

<0.0001

Cyp27a1

Cytochrome P450, family 27, subfamily a, polypeptide 1

1

D1Mit215

BW

FPW

Adipose tissue

1.2

0.10

Irs1

Insulin receptor substrate 1

1

D1Mit215

BW

FPW

Adipose tissue

0.6

0.05

Mogat1

Monoacylglycerol O-acyltransferase 1

1

D1Mit215

FPW

Adipose tissue

0.2

0.0002

Usp37

Ubiquitin specific peptidase 37

1

D1Mit215

BW

FPW

Adipose tissue

1.0

0.90

Spag5

Sperm associated antigen 5

11

D11Mit41

Tg

Muscle

1.02

0.95

Ccl9

Chemokine (C-C motif) ligand 9

11

D11Mit41

BW

FPW

Adipose tissue

2.2

0.01

Ccl6

Chemokine (C-C motif) ligand 6

11

D11Mit41

BW

FPW

Adipose tissue

1.4

0.20

Ccl3

Chemokine (C-C motif) ligand 3

11

D11Mit41

BW

FPW

Adipose tissue

5.5

<0.0001

Msi2

Musashi homolog 2 (Drosophila)

11

D11Mit41

Tg

Muscle

1.03

0.75

Agtr1b

Angiotensin II receptor, type 1b

3

D3Mit304

Tg

Muscle

1.11

0.85

Pik3ca

Phosphatidylinositol 3-kinase, catalytic, alpha polypeptide

3

D3Mit304

Tg

Muscle

0.91

0.24

Ccdc39

Coiled-coil domain containing 39

3

D3Mit304

Tg

Muscle

0.66

0.40

Ccdc79

Coiled-coil domain containing 79

8

D8Mit242

Tg

Muscle

0.59

0.40

Apoa2

Apolipoprotein A-II

1

D1Mit113

Tg

Chol

Liver

1.07

0.08

Insig2

Insulin induced gene 2

1

D1Mit113

Tg

Chol

Muscle

0.95

0.73

Zfp69

Zinc finger protein 69

4

D4Mit312

Glu

Adipose tissue

2.2

0.03


Chr, chromosome; Fold, the fold change in TH vs. B6 (TH/B6); Tg, triglyceride; Chol, cholesterol; Glu, glucose; FPW, fat pad weight; BW, body weight.

Stewart et al. BMC Genomics 2010 11:713   doi:10.1186/1471-2164-11-713

Open Data