Table 5

Correlations of the gene expression levels with physiological traits.

Tissue

Positively

correlated

Negatively

correlated

Trait


Near D1Mit113

Adipose tissue

Prrx1, Creg1, Nuf2, Sh2d1b1, Fcgr4, Fcgr3, Fcer1g, Adamts4, Cd84, Pea15a, Atp1a4, Slamf9, Tagln2, Vsig8, Slamf8, Wdr26, Degs1, Kctd3, Atf3

Gas5, Opn3, Sdccag8, Hnrnpu, Trp53bp2, Iars2, Ptpn14

BW

FPW

Muscle

Sft2d2, Dedd,

Sdhc

Mrps14, Prrx1, Nme7, Mpzl1, Cd247, Lrrc52, Fcrla,

Adamts4, Pvrl4, Cd244, Slamf7, Igsf9, Tagln2

Chol

Tg


Near D11Mit132

Adipose tissue

Ccl6, Rab5c, Atp6v0a1, Psmc3ip, Tubg1, Psme3, Dusp3, Grn, Nmt1, Plekhm1, Cdc27, Mrc2, Tanc2, Wipi1, Kpna2

Stat5b, Rdm1, Rprml, Helz

BW

FPW

Muscle

Prkar1a, Sgca, Spop, Krtap3-1

Fkbp10, Acly, Stat3, Vps25, Cntd1, Psme3, Ifi35, Brca1, Slc25a39, Gpatch8, Gm1564, Eftud2, Hexim2, Lyzl6, Wnt3, Crhr1, Arsg, Slfn10, Slfn3, Kal1, Lhx1, Ggnbp2, Usp32, Ptrh2, Dhx40, Rad51c, Msi2, Car10, Mbtd1, Mycbpap, Rsad1, Hils1, Zfp652, Ube2z, Calcoco2, Skap1, Scrn2, Kpnb1, Pip4k2b, Med1, Crkrs, Gsdma2, Wipf2, Krt12

Tg


Near D4Mit178

Adipose tissue

Col15a1, Nipsnap3a, Svep1, Slc31a1, Orm1, Tnc, Megf9, Mpdz

Rgs3, Orm3

BW

FPW

Muscle

Mup4, Mup3, Zfp37, Orm2, Pappa, Dbc1, Cdk5rap2, Rasef

Tg


Near D8Mit242

Adipose tissue

Tmem208, Lypla3, Cyb5b, Hp, Mlkl, Cenpn, Gcsh, Cotl1, Gins2

Cirh1a, Ces3, Bbs2, Terf2ip, Fbxo31

BW

FPW

Muscle

Cog8, Znrf1, Gse1

Cdh8, Cklf, Cmtm2a, Ccdc79, Lcat, Prmt7, Sntb2, Adat1, Terf2ip, Mon1b, Jph3, Cdt1, Zfp319, Gins3, Setd6

Tg


Near D3Mit304

Muscle

Agtr1b, Tbl1xr1, Arpm1, Samd7, Cldn11, Slc7a14, Pik3ca, Ccdc39, Sox2

Tg

Adipose tissue

Fabp5, Sirpb1, Aadacl1, Tpd52

Lrrcc1, Car3, Mynn, Phc3, Zfhx4

BW

FPW


Near D4Mit312

Muscle

Nadk

Eif4g3, Ubxd3, Pax7, Arhgef19, Tnfrsf8, Rex2, Clcn6, Fbxo6, Gpr153, Morn1, Gabrd, Ssu72, Ttll10, Dhdds, Lin28, Sepn1, Srrm1, Rcan3, Cnr2, Htr1 d, Ephb2, Ptafr, Eya3

Tg

Adipose tissue

Efhd2, Lzic, Pgd, Plod1, Dnajc16, Necap2, Mfap2, Atp13a2, Igsf21, Capzb, Pla2g2e, Hspg2, C1qc, Ephb2, Clic4, Ldlrap1, Paqr7, Stmn1

Sdf4, Thap3, Per3, Park7, H6pd, Tmem201, Tardbp, Gale, Srrm1, Syf2, Tmem57

BW

FPW


Near D11Mit41

Adipose tissue

Eif4a1, Atp6v0a1, Psmc3ip, Dusp3, Nmt1, Mpdu1, Cd68, Garnl4, Serpinf1, Slc43a2, Pitpna, Blmh, Pigs, Evi2a, Rhbdl3, Ccl2, Ccl7, Ccl9, Ccl6, Ccl3, Dynll2, Mmd, Lrrc59, Col1a1, Top2a

Rdm1, Ssh2, Unc45b, Acaca, Ggnbp2, Med13, Vezf1,

Tmem100, Spop, Kpnb1, Erbb2, Thra,

BW

FPW

Muscle

Sgca, Spop, Krtap3-1

Fkbp10, Acly, Cntd1, Ifi35, Lyzl6, Aurkb, Trp53, Alox12, Itgae, Phf12, Nek8, Spag5, Nos2, Rhot1, Zfp207, Fndc8, Slfn10, Slfn3, Kal1, Lhx1, Ggnbp2, Usp32, Ptrh2, Dhx40, Rad51c, Msi2, Car10, Mbtd1, Mycbpap, Rsad1, Hils1, Zfp652, Ube2z, Calcoco2, Skap1, Scrn2, Kpnb1, Pip4k2b, Crkrs, Gsdma2, Wipf2, Krt12

Tg


Near D1Mit215

Adipose tissue

Slc11a1, Col6a3

Ikzf2, Usp37, Cyp27a1, Mogat1, Irs1

BW

FPW

Liver

Igfbp2

FPW

Muscle

Sumo1, Spag16, Tnp1, Vil1, Plcd4, Zfp142, Ttll4, Cyp27a1, Des, Epha4, Pax3, Mrpl44, Cops7b, Chrng

Tg


Near D14Mit107

Adipose tissue

Dock9

BW

FPW

Muscle

Dock9, Dzip1, Oxgr1, Ipo5, Farp1, Fgf14,

Tg


Genes located in physiological trait QTL intervals, showing correlations of the gene expression levels with physiological traits (P < 0.05) are detected by microarray and regression analyses using the subset of F2 mice (n = 16). Genes in bold are confirmed by qRT-PCR. BW, body weight; FPW, fat pad weight; Chol, cholesterol; Tg, triglyceride.

Stewart et al. BMC Genomics 2010 11:713   doi:10.1186/1471-2164-11-713

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