Table 4

Translation initiation factors down regulated in myo1Δ strains.

Initiation Factor/Gene Names

Function (http://www.yeastgenome.org webcite)

Fold Change in Microarray (p≤0.01)

Fold Change by Real Time RT-PCR (± s.d.)


eIF1Ad (TIF11)

Forms a complex with Sui1p (eIF1) and the 40 S ribosomal subunit and scans for the start codon

-2.41

-2.52 ± 0.42

eIF2γ (GCD11)

Identification of the start codon

-1.43

-1.26 ± 0.21

eIF2Bβ (GCD7)

Guanine-nucleotide exchange factor for eIF2

-1.29

-1.38 ± 0.27

eIF5 (TIF5)

GTPase-activating protein mediates hydrolysis of ribosome-bound GTP

-1.25

-1.60 ± 0.47

eIF4A (TIF2)

RNA helicase

-1.32

-2.14 ± 0.50

eIF3β (PRT1)

Binding of mRNA and Met- tRNAi to ribosomes

-1.39

-1.87 ± 0.10


Rivera-Ruiz et al. BMC Genomics 2010 11:690   doi:10.1186/1471-2164-11-690

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