Overlap of TR4 target genes in 4 cell types. A target gene is defined as the nearest gene to a ChIP-seq peak. In some cases a target gene was contained more than one peak. Genome-wide TR4 ChIP-seq has identified 535 target genes in K562, 1,688 in HepG2, 1,135 in HeLa, and 530 in GM12878 cells within ± 1 kb of a transcription start site. 332 genes are identified as common targets in the 4 cell types.
O'Geen et al. BMC Genomics 2010 11:689 doi:10.1186/1471-2164-11-689