Table 2

Genes with most prominent changes in expression levels#.

WC 3 h

WCCo 3 h

CoCl2 3 h

WC 3 d

WCCo 3 d

CoCl2 3 d

Gene Name

Accession

Description


up

up

up

up

up

PPFIA4

NM_015053

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 (PPFIA4), mRNA [NM_015053]


up

up

up

up

BNIP3

NM_004052

BCL2/adenovirus E1B 19 kDa interacting protein 3 (BNIP3), nuclear gene encoding mitochondrial protein, mRNA [NM_004052]


up

up

up

up

PDK1

NM_002610

pyruvate dehydrogenase kinase, isozyme 1 (PDK1), nuclear gene encoding mitochondrial protein, mRNA [NM_002610]


up

up

up

CA9

NM_001216

carbonic anhydrase IX (CA9), mRNA [NM_001216]


up

up

up

EGLN3

NM_022073

egl nine homolog 3 (C. elegans) (EGLN3), mRNA [NM_022073]


up

up

up

LOXL2

NM_002318

lysyl oxidase-like 2 (LOXL2), mRNA [NM_002318]


up

up

up

THC2369600

THC2369600

ALU6_HUMAN (P39193) Alu subfamily SP sequence contamination warning entry, partial (12%) [THC2369600]


up

up

PLOD2

NM_182943

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), transcript variant 1, mRNA [NM_182943]


up

up

PPP1R3C

NM_005398

protein phosphatase 1, regulatory (inhibitor) subunit 3C (PPP1R3C), mRNA [NM_005398]


up

up

CST6

NM_001323

cystatin E/M (CST6), mRNA [NM_001323]


up

up

FN1

NM_212482

fibronectin 1 (FN1), transcript variant 1, mRNA [NM_212482]


up

up

THC2316753

THC2316753

Q91TG6 (Q91TG6) T130, partial (7%) [THC2316753]


up

up

VLDLR

NM_003383

very low density lipoprotein receptor (VLDLR), transcript variant 1, mRNA [NM_003383]


up

up

AML1a

ENST00000358356

mRNA for AML1a protein, complete cds. [D43967]


up

up

HK2

NM_000189

hexokinase 2 (HK2), mRNA [NM_000189]


up

up

PTGS2

NM_000963

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2), mRNA [NM_000963]


up

up

SLC2A14

BC060766

solute carrier family 2 (facilitated glucose transporter), member 14, mRNA (cDNA clone MGC:71510 IMAGE:5297510), complete cds. [BC060766]


up

up

GPI

NM_000175

glucose phosphate isomerase (GPI), mRNA [NM_000175]


up

up

ENO2

NM_001975

enolase 2 (gamma, neuronal) (ENO2), mRNA [NM_001975]


up

up

CDH2

NM_001792

cadherin 2, type 1, N-cadherin (neuronal) (CDH2), mRNA [NM_001792]


up

up

AK021874

ENST00000366930

cDNA FLJ11812 fis, clone HEMBA1006364. [AK021874]


up

up

up

up

ASB2

NM_016150

ankyrin repeat and SOCS box-containing 2 (ASB2), mRNA [NM_016150]


up

up

up

up

ANGPTL4

NM_139314

angiopoietin-like 4 (ANGPTL4), transcript variant 1, mRNA [NM_139314]


up

up

up

LOC653068

XM_925841

PREDICTED: similar to TBP-associated factor 9L (LOC653068), mRNA [XM_925841]


up

up

TCF19

BC033086

transcription factor 19 (SC1), mRNA (cDNA clone MGC:45652 IMAGE:3160434), complete cds. [BC033086]


up

up

AIPL1

NM_014336

aryl hydrocarbon receptor interacting protein-like 1 (AIPL1), transcript variant 1, mRNA [NM_014336]


up

up

LOC200726

XM_117266

PREDICTED: hypothetical LOC200726 (LOC200726), mRNA [XM_117266]


up

up

LUZPP1

AJ312775

mRNA for leucine zipper protein 3 (LUZP3 gene). [AJ312775]


up

C9orf65

NM_138818

chromosome 9 open reading frame 65 (C9orf65), mRNA [NM_138818]


up

THC2411387

THC2411387

ALU8_HUMAN (P39195) Alu subfamily SX sequence contamination warning entry, partial (9%) [THC2411387]


up

SOX6

NM_033326

SRY (sex determining region Y)-box 6 (SOX6), transcript variant 2, mRNA [NM_033326]


up

SULT2A1

NM_003167

sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (SULT2A1), mRNA [NM_003167]


up

C1orf67

BC042869

cDNA clone IMAGE:5270407. [BC042869]


up

CRB1

NM_201253

crumbs homolog 1 (Drosophila) (CRB1), mRNA [NM_201253]


up

up

EDN2

NM_001956

endothelin 2 (EDN2), mRNA [NM_001956]


up

CBLN4

NM_080617

cerebellin 4 precursor (CBLN4), mRNA [NM_080617]


up

G65686

ENST00000332107

A117 Human STS cDNA, sequence tagged site. [G65686]


up

XAGE2

NM_130777

X antigen family, member 2 (XAGE2), mRNA [NM_130777]


up

PELO

AF118075

PRO1770 mRNA, complete cds. [AF118075]


up

SAA3P

AY209188

truncated serum amyloid A3 precursor (SAA3) mRNA, complete cds. [AY209188]


up

ITIH5

NM_030569

inter-alpha (globulin) inhibitor H5 (ITIH5), transcript variant 1, mRNA [NM_030569]


up

MCHR1

NM_005297

melanin-concentrating hormone receptor 1 (MCHR1), mRNA [NM_005297]


up

MGAT4A

NM_012214

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A (MGAT4A), mRNA [NM_012214]


up

GPR65

NM_003608

G protein-coupled receptor 65 (GPR65), mRNA [NM_003608]


up

DFNB31

AK056190

cDNA FLJ31628 fis, clone NT2RI2003344, weakly similar to PRESYNAPTIC PROTEIN SAP97. [AK056190]


up

LRP8

NM_033300

low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), transcript variant 2, mRNA [NM_033300]


dn

up

up

up

SORCS3

NM_014978

sortilin-related VPS10 domain containing receptor 3 (SORCS3), mRNA [NM_014978]


dn

up

HLA-DPA1

NM_033554

major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1), mRNA [NM_033554]


up

dn

dn

AKR1C1

BC040210

aldo-keto reductase family 1, member C1, mRNA (cDNA clone MGC:42600 IMAGE:4825338), complete cds. [BC040210]


up

dn

up

WDR64

NM_144625

WD repeat domain 64 (WDR64), mRNA [NM_144625]


dn

up

ESCO2

NM_001017420

establishment of cohesion 1 homolog 2 (S. cerevisiae) (ESCO2), mRNA [NM_001017420]


dn

up

CACNG5

NM_145811

calcium channel, voltage-dependent, gamma subunit 5 (CACNG5), transcript variant 1, mRNA [NM_145811]


dn

up

ANPEP

NM_001150

alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) (ANPEP), mRNA [NM_001150]


dn

up

GPX7

NM_015696

glutathione peroxidase 7 (GPX7), mRNA [NM_015696]


dn

dn

up

TTLL7

NM_024686

tubulin tyrosine ligase-like family, member 7 (TTLL7), mRNA [NM_024686]


dn

dn

up

THC2371963

THC2371963

AIP1_HUMAN (Q86UL8) Atrophin-1 interacting protein 1 (Atrophin-1 interacting protein A) (MAGI-2), partial (3%) [THC2371963]


up

dn

dn

GDF15

NM_004864

growth differentiation factor 15 (GDF15), mRNA [NM_004864]


dn

dn

ALDH1A1

NM_000689

aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), mRNA [NM_000689]


dn

dn

DCN

NM_001920

decorin (DCN), transcript variant A1, mRNA [NM_001920]


dn

dn

SOX2

NM_003106

SRY (sex determining region Y)-box 2 (SOX2), mRNA [NM_003106]


dn

dn

TAF9B

NM_015975

TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31 kDa (TAF9B), mRNA [NM_015975]


dn

dn

THC2302184

THC2302184

GAL2_HUMAN (Q01415) N-acetylgalactosamine kinase (GalNAc kinase) (Galactokinase 2), partial (21%) [THC2302184]


dn

dn

PTPRZ1

NM_002851

protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1), mRNA [NM_002851]


dn

dn

DMRT2

NM_006557

doublesex and mab-3 related transcription factor 2 (DMRT2), transcript variant 1, mRNA [NM_006557]


dn

dn

CLEC3A

NM_005752

C-type lectin domain family 3, member A (CLEC3A), mRNA [NM_005752]


dn

dn

ATP10B

AB018258

mRNA for KIAA0715 protein, partial cds. [AB018258]


dn

dn

PROS1

NM_000313

protein S (alpha) (PROS1), mRNA [NM_000313]


dn

dn

RAXLX

NM_001008494

RAX-like homeobox (RAXLX), mRNA [NM_001008494]


dn

dn

OLFM4

NM_006418

olfactomedin 4 (OLFM4), mRNA [NM_006418]


dn

dn

DSG4

NM_177986

desmoglein 4 (DSG4), mRNA [NM_177986]


dn

dn

dn

IQGAP2

NM_006633

IQ motif containing GTPase activating protein 2 (IQGAP2), mRNA [NM_006633]


dn

dn

dn

MAL

NM_002371

mal, T-cell differentiation protein (MAL), transcript variant a, mRNA [NM_002371]


dn

dn

dn

KRT1

NM_006121

keratin 1 (epidermolytic hyperkeratosis) (KRT1), mRNA [NM_006121]


dn

dn

dn

MMP1

NM_002421

matrix metallopeptidase 1 (interstitial collagenase) (MMP1), mRNA [NM_002421]


dn

dn

dn

LAMP3

NM_014398

lysosomal-associated membrane protein 3 (LAMP3), mRNA [NM_014398]


dn

dn

dn

HLA-DMB

NM_002118

major histocompatibility complex, class II, DM beta (HLA-DMB), mRNA [NM_002118]


dn

dn

dn

HERC5

NM_016323

hect domain and RLD 5 (HERC5), mRNA [NM_016323]


dn

BTN3A3

NM_006994

butyrophilin, subfamily 3, member A3 (BTN3A3), transcript variant 1, mRNA [NM_006994]


dn

C6orf130

NM_145063

chromosome 6 open reading frame 130 (C6orf130), mRNA [NM_145063]


dn

CRY2

NM_021117

cryptochrome 2 (photolyase-like) (CRY2), mRNA [NM_021117]


dn

TMEM140

NM_018295

transmembrane protein 140 (TMEM140), mRNA [NM_018295]


dn

ZNF438

NM_182755

zinc finger protein 438 (ZNF438), mRNA [NM_182755]


dn

DNMT3L

NM_013369

DNA (cytosine-5-)-methyltransferase 3-like (DNMT3L), transcript vari ant 1, mRNA [NM_013369]


dn

CTAGE3

AF338231

CTAGE-3 protein mRNA, complete cds. [AF338231]


dn

MOSPD2

NM_152581

motile sperm domain containing 2 (MOSPD2), mRNA [NM_152581]


dn

OR4N4

NM_001005241

olfactory receptor, family 4, subfamily N, member 4 (OR4N4), mRNA [NM_001005241]


dn

SPATA7

NM_018418

spermatogenesis associated 7 (SPATA7), transcript variant 1, mRNA [NM_018418]


dn

TMC1

NM_138691

transmembrane channel-like 1 (TMC1), mRNA [NM_138691]


# listed genes were statistically significant different and exhibited at least a 5fold induction or repression in one of the treatments (with respect to controls and based on normalised fluorescence intensity ratios in the microarray analysis); type of gene regulation is indicated as "up" for induction (> 2fold) and "dn" for repression (> 2fold); fields are empty when induction or repression was < 2fold; full table is provided as Additional File 1

Busch et al. BMC Genomics 2010 11:65   doi:10.1186/1471-2164-11-65

Open Data