Table 1

General sequence properties of human genes

imprinted

maternally expressed

paternally expressed

autosomal


G+C content of genes

46.56%

46.91%

45.98%

45.47%


CpGobs/CpGexp of genes

0.305

0.305

0.315

0.280


gene length (bp)

29641

46976

26829

22422


intron length (bp)

1637*

1652

1633

1549


length of intergenic regions (bp)

50879*

49483

55322

26410


coverage of introns with purely intronic PCSs

0.74%

0.69%

1.09%

0.45%


purely intronic PCSs per 10 kb of intron per gene

1.72

1.35

2.04

1.06


coverage of intergenic regions with PCSs

0.66%

0.74%

0.64%

1.11%


intergenic PCSs per 10 kb per gene

1.29

1.41

1.29

2.17


* p < 0.01 (Wilcoxon test for comparison with autosomal genes)

Gene length: length of transcribed DNA sequence from most upstream transcriptional start site to most downstream transcriptional termination site; intergenic region: For this, the intergenic segments between any two genes were cut into two halves. Each of them was assigned to the closest gene. As intergenic region of a gene we then added the lengths of the halved upstream intergenic segment and of the halved downstream intergenic segment. Since the features show a highly skewed distribution, medians are given instead of averages and standard deviations.

Hutter et al. BMC Genomics 2010 11:649   doi:10.1186/1471-2164-11-649

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