Table 1

Characteristics of polyadenylation regions used for recognition of PAS-strong, PAS-weak and PAS-less sites, and Mahalonobis distance (D2; 38) showing the power of recognition of each characteristic

Characteristics

D2 for PAS-strong sites

D2 for PAS-weak sites

D2 for PAS-less sites


PAS-motif, [-40: -1]

3.18

1.98

CS-motif*

1.15

1.51

1.36

GU/U-motif, [+1: +50]

1.08

0.90

0.48

Upstream Pentamer Composition

0.72

0.52

0.83

Downstream Pentamer Compositionc

0.84

1.32

PAS-CS distance

1.24

0.77

CS-GT distance

0.30

0.24

0.17


Total D2:

7.67

6.75

4.16


* Location of CS-motif: [-15: +3] for PAS-strong and PAS-weak sites; [-9: +3] for PAS-less sites.

Akhtar et al. BMC Genomics 2010 11:646   doi:10.1186/1471-2164-11-646

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