Additional file 13.
Figure S4. Hierarchical clustering. Using IBD distances calculated in software Plink, Ward agglomerative clustering (done in R) reveals a large cluster (A) of Scandinavian and western Europeans on the left. Smaller clusters on the right include (B) Eastern European (Russian and Polish) Ashkenazi Jews, (C) Mediterranean/Western European, (D) Hispanic with some Mediterranean, (E) Mediterranean, (F) non-Ashkenazi Eastern European. Self-reported ethnicity data was available for about 1/3 of the samples. This data is shown below the clusters. A red dot on the "Polish" row means that the person reports being Polish. A black dot means that the person did not report being Polish. The grey background means that no self-reported data was available for that person. Just above the self-reported ethnicity rows (black and red) is a single row showing cohort. Each sample belonged to one of three cohorts (UCSF = green, BWH = black, CMS = red). Note that nearly all samples from the non-western European group (B-F) came from the UCSF cohort.
Format: TIFF Size: 1.5MB Download file
Khankhanian et al. BMC Genomics 2010 11:626 doi:10.1186/1471-2164-11-626