Figure 4.

IPA network depicting relationships among pro-inflammatory genes in cluster 2, 3 hours post-infestation with P. ovis. Merged representation of the four highest scoring networks. Individual nodes represent protein functions with relationships represented by edges. Nodes coloured by gene expression, red indicating up-regulation and white indicating gene/factor not differentially expressed but with defined relationship to other genes in network. Arrows indicate directional relationships. Red circles highlight roles for IL1A, IL1B, IL6, NF-kB, TLR2 and TLR4. Only direct interactions selected

Burgess et al. BMC Genomics 2010 11:624   doi:10.1186/1471-2164-11-624
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