Sources of variation & lists of differentially expressed genes in breast cancer. A. Estimated measures of significance of the sources of variation in gene expression data in FF samples. B. Estimated measures of significance of the sources of variation in gene expression data in FFPE samples. C. Venn diagram showing overlap between three lists of differentially expressed genes (at FDR 0.05 level and at least 2-fold) in breast cancer tissue compared to corresponding adjacent normal breast tissue from three different analyses -using only FF samples (top center, showing 1275 genes), using only FFPE samples (bottom left, showing 966 genes) and using both the FF and FFPE samples in a combined analysis (bottom right, showing 1319 genes).
Kibriya et al. BMC Genomics 2010 11:622 doi:10.1186/1471-2164-11-622