Depletion of H3K27 tri-methylation in domains containing female-biased coding and non-coding genes. The figure shows enrichment of the repressive histone mark H3K27me3 in female and male mouse liver in the identified domains containing a coding X-inactivation escapee gene and a female-biased lncRNA, and the neighbouring regions. Rps4x is included for comparison with an X-inactivated gene. Red colour designates coding genes and green colour designates non-coding genes. The numbers 1-4 above the graphs correspond to the four female-biased clusters in Figure 3 and 4. GEO accession: GSE20617, NCBI37/mm9 genome assembly.
Reinius et al. BMC Genomics 2010 11:614 doi:10.1186/1471-2164-11-614