DNA-Seq coverage profiles of X chromosome and autosome gene features. (A-H) The average sequence coverage profiles of exon/intron regions and regions near transcription start sites (TSS) and termination sites (TTS) of all annotated gene models on the X chromosome (red), major autosomes (black), and the dot chromosome 4 (blue) in male (A-D) and female (E-H) adult flies. Male X chromosome coverage was multiplied by two to correct for karyotype. Significance of the chromosome arm distributions relative to the whole genome data set as determined by permutation sampling and KS test for females (I-L). P Values < 10-15 are off-scale (black arrow).
Zhang and Oliver BMC Genomics 2010 11:6 doi:10.1186/1471-2164-11-6