Open Access Research article

Expression profiling of S. pombe acetyltransferase mutants identifies redundant pathways of gene regulation

Rebecca L Nugent1, Anna Johnsson2, Brian Fleharty3, Madelaine Gogol3, Yongtao Xue-Franzén2, Chris Seidel3, Anthony PH Wright2 and Susan L Forsburg1*

  • * Corresponding author: Susan L Forsburg forsburg@usc.edu

  • † Equal contributors

Author Affiliations

1 Molecular and Computational Biology Section, University of Southern California, Los Angeles, California 90089-2910, USA

2 Center for Biosciences, Department of Biosciences and Nutrition, Karolinska Institutet, S-141-57 Huddinge, Sweden and School of Life Sciences, Södertörn University, S-141 89 Huddinge, Sweden

3 Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA

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BMC Genomics 2010, 11:59  doi:10.1186/1471-2164-11-59

Published: 22 January 2010

Additional files

Additional file 1:

GO terms differentially regulated in HAT mutants. This table lists the down and up-regulated gene ontology (GO) terms of mutant HATs.

Format: PDF Size: 72KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 2:

Differentially regulated genes (3.25 fold) in the triple HAT mutant. This table lists the down and up-regulated genes of the triple HAT mutant compared to wild-type using an Affymetrix microarray.

Format: PDF Size: 46KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 3:

Differentially expressed genes (3.25 fold) in double HAT mutants. This table lists the differentially changed genes in the double HAT mutants compared to wild-type using an Affymetrix microarray.

Format: PDF Size: 72KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 4:

Genes with 2 fold change in gene expression after exposure to salt. This table lists the down and up-regulated genes after addition of salt using of mutant HATs using an Eurogentech microarray.

Format: PDF Size: 232KB Download file

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Open Data

Additional file 5:

Differentially expressed gene (1.7 fold) in HAT mutants. This table lists the differentially changed genes in the HAT mutants compared to wild-type using an Affymetrix microarray.

Format: PDF Size: 596KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data