Principal Component Analysis (PCA) plot of microarray samples and genes. Left image shows PCA of LEC vs ALL samples following feature subset analysis performed on Jexpresspro software. The LEC samples are represented as green dots and rest of the samples as blue dots. LEC biological replicates are seen to cluster separately from rest of the samples indicating differences between LEC and other sample groups but similarity or reproducibility between LEC replicates. Right image shows PCA of differentially expressed genes (527) between LEC and cornea. These are clustered into four distinct coloured groups according to the density. The red group has the highest density and blue the lowest, black dots in the centre are unclustered genes.
Kulkarni et al. BMC Genomics 2010 11:526 doi:10.1186/1471-2164-11-526