Open Access Highly Accessed Research article

Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation

Márcia M Aranha1, Daniela M Santos1, Joana M Xavier1, Walter C Low23, Clifford J Steer45, Susana Solá1 and Cecília MP Rodrigues1*

Author Affiliations

1 Research Institute for Medicines and Pharmaceutical Sciences, Faculty of Pharmacy, University of Lisbon, Lisbon 1649-003, Portugal

2 Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA

3 Stem Cell Institute, University of Minnesota Medical School, Minneapolis, MN 55455, USA

4 Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA

5 Department of Genetics, Cell Biology, and Development, University of Minnesota Medical School, Minneapolis, MN 55455, USA

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BMC Genomics 2010, 11:514  doi:10.1186/1471-2164-11-514

Published: 24 September 2010

Additional files

Additional file 1:

Clustering analysis. Clustering analysis of differentiated mouse NS cells based on apoptosis-associated miRNA expression levels at 1, 3 and 8 days.

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Additional file 2:

Flow cytometry analysis. Forward scatter/side scatter (FSC/SSC) distribution of mouse NS cells. Unstained controls, in which incubation with primary antibody was avoided, were performed to determine the limit at which fluorescence intensity can be considered specific.

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