Sum1 is important for NDT80 repression. A: Western Blot of Ndt80-myc during meiosis in WT and sum1Δ strains. Note the high levels of Ndt80 in late meiosis in the sum1Δ strain. Meiosis Stages are indicated below the blots. B: Results of ChIP-PCR on Ndt80-myc for the promoter of NDT80 in sum1Δ cells at 15 hours in sporulation medium. Ndt80 binds to its own promoter when Sum1 is absent.
Klutstein et al. BMC Genomics 2010 11:478 doi:10.1186/1471-2164-11-478