Methodology article
A novel tissue-specific meta-analysis approach for gene expression predictions, initiated with a mammalian gene expression testis database
- † Equal contributors
1 Institute of Bioinformatics and Applied Biotechnology (IBAB), Biotech Park, Electronic City, Bangalore - 560100, Karnataka state, India
2 Shodhaka Life Sciences Pvt. Ltd., IBAB, Biotech Park, Bangalore - 560100, India
BMC Genomics 2010, 11:467 doi:10.1186/1471-2164-11-467
Published: 11 August 2010Additional files
Additional file 1:
Notes S1. Details of gene-set collection and fixed vocabulary usage in the database creation.
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Additional file 2:
Table S1. Illustration of scoring derived from multiple data sets for specific ESLCs ('transcribed' or 'dormant' in normal human adult testis).
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Additional file 3:
Figure S1. Schematic representation of creation and functioning of MGEx-Tdb.
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Additional file 4:
Table S2. References and URLs for various databases/repositories used/referred in the study.
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Additional file 5:
Table S3. Summary of manually curated data (MCD, from reports on individual gene studies) for the genes selected for final comparison of databases.
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Additional file 6:
Table S4. Scoring method for assessing the extent of agreement between the manually curated data (MCD, from reports on individual gene studies) vs. the information from databases.
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Additional file 7:
Notes S2. Procedure for comparison of MCD with the information from the databases.
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Additional file 8:
Table S5. Procedure for relative assessment of amount and details of information, and agreement with reports from individual gene studies.
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Additional file 9:
Notes S3. Procedure for comparison of results from various resources for gene expression under different physiological conditions and developmental stages in testis.
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Additional file 10:
Notes S4. An overview of MGEx-Tdb use, with the help of screen-shots.
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