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Open Access Highly Accessed Research article

Comparative metagenomic analysis of plasmid encoded functions in the human gut microbiome

Brian V Jones1*, Funing Sun2 and Julian R Marchesi23

Author Affiliations

1 Centre for Biomedical and Health Sciences Research, School of Pharmacy and Biomolecular Sciences, University of Brighton, Lewes Road Brighton, UK

2 Alimentary Pharmabiotic Centre and Dept of Microbiology, University College Cork, College Road, Cork, Ireland

3 Cardiff School of Biosciences, Cardiff University, Park Place, Cardiff, UK

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BMC Genomics 2010, 11:46  doi:10.1186/1471-2164-11-46

Published: 19 January 2010

Additional files

Additional file 1:

Table S1 - Detailed summary of pTRACA18, pTRACA20, pTRACA22, and pTRACA30 open reading frames and putative functions. Detailed information on putative functions and homologies of predicted open reading frames identified in plasmids pTRACA18, pTRACA20, pTRACA22 and pTRACA30.

Format: DOCX Size: 26KB Download file

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Additional file 2:

Table S1 - Sequences represented in Figure 6. Accession numbers of RelE amino acid sequences used in Figure 6. Sequences retrieved from human gut metagenomic datasets are included and those harbouring complete putative RelBE modules, orphan RelE toxin genes, and potentially novel antitoxin components are indicated.

Format: DOCX Size: 16KB Download file

Open Data