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Open Access Highly Accessed Research article

Microarray Analysis of Response of Salmonella during Infection of HLA-B27- Transfected Human Macrophage-Like U937 Cells

Shichao Ge1, Vittoria Danino2, Qiushui He1, Jay CD Hinton2 and Kaisa Granfors1*

Author Affiliations

1 Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare, Turku, Finland

2 Molecular Microbiology Group, Institute of Food Research, Colney, Norwich, UK

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BMC Genomics 2010, 11:456  doi:10.1186/1471-2164-11-456

Published: 30 July 2010

Additional files

Additional file 1:

Supplemental Tables S1- 6 - Global gene expression of S. Enteritidis PT4 in HLA-B27- or HLA-A2-transfected cells using microarray assay. The Supplemental Tables S1-6 contain gene expression profiles of S. Enteritidis PT4 strain during infection of U937 cells (Table S1), genes up- or down-regulated more than two-fold in HLA-A2-transfected U937 cells compared to LB culture at 2 h after infection (Tables S2-1, -2), in HLA-B27-transfected cells compared to LB culture at 2 h after infection (Table S3-1,-2), in HLA-A2-transfected U937 cells compared to LB culture at 8 h after infection (Tables S4-1, -2), in HLA-B27-transfected cells compared to LB culture at 8 h after infection (Table S5-1,-2) and in HLA-B27-transfected cells compared to HLA-A2-transfected cells at 8 h after infection (Tables S6-1, -2).

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Additional file 2:

Supplemental Tables S7 and S8 - The correlation analysis between PT-PCR and array data and the expression of the gene rfaH in different conditions. The Supplemental Tables S7 and S8 contain the correlation analysis between PT-PCR and array data (Table S7) and the expression of the gene rfaH in different conditions (Table S8).

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