Figure 6.

Mapping of IKZF1 (IKAROS) deletions at 1 kb resolution. Customized oligonucleotide aCGH results for IKZF1 (Ikaros) (exons 1-8, highlighted) for 9 CML/BCL samples. Cases 156 & 163 (arrowed) are reported normal by 105 K arrays, while the rest are deleted. The genome address is given on the left, where the large blue cross lines indicate the position of 105 K probes. Vertical lines represent results for each case - the hair lines map losses at a resolution of ~1 Kb. The two data sets are consistent for all samples but one (case 163), where the high resolution array revealed deletion of exon 3 only (red arrow), missed by 105 K array

Nacheva et al. BMC Genomics 2010 11:41   doi:10.1186/1471-2164-11-41
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