Estimate of the method accuracy with GO: D. melanogaster vs. S. cerevisiae. Accuracy achieved on the MF (left) and BP (right) ontologies when using sequence information alone (orange curves, for different e-value cutoffs) and when exploiting the expression context (blue curves, for different ξ thresholds). The x-axis shows the number of gene pairs authorizing annotation transfers. (a) Results achieved on RBH gene pairs. (b) Results achieved on gene pairs with potentially low sequence similarity.
Bréhélin et al. BMC Genomics 2010 11:35 doi:10.1186/1471-2164-11-35