Additional file 1.
Regulation of the cardiomyocyte global transcriptome by ET-1 or insulin (Microsoft Word Table). Cardiomyocytes were unstimulated (control), or exposed to 100 nM ET-1 or 50 mU/ml insulin (1 h). Total RNA expression was determined using microarrays. Transcripts were identified with significant changes in expression (>1.5-fold change induced by ET-1 or insulin relative to controls; FDR < 0.05, * ET-1 vs control; # Insulin vs control; † ET-1 vs insulin, one-way ANOVA with Tukey post-test and Benjamini-Hochberg FDR correction). Mean raw values are given for controls with the mean change relative to controls for ET-1 or insulin (n = 4). For transcripts represented by more than one probeset, the probesets and corresponding raw values are listed with the average of the mean relative change. RNA responses are clustered according to up- or down-regulation, and the effect of ET-1 and/or insulin. Clusters (i) - (viii) correspond to the summarised data in Figure 2A of the associated manuscript. Clusters are colour-coded according to response to ET-1 and insulin (green), ET-1 only (yellow) or insulin only (cyan). AS, Antisense.
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Markou et al. BMC Genomics 2010 11:343 doi:10.1186/1471-2164-11-343