Open Access Highly Accessed Research article

Bioinformatic identification and characterization of human endothelial cell-restricted genes

Manoj Bhasin12, Lei Yuan234, Derin B Keskin5, Hasan H Otu2, Towia A Libermann12 and Peter Oettgen234*

Author Affiliations

1 Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA 02215, USA

2 Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA 02215, USA

3 Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA 02215, USA

4 Division of Molecular and Vascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA 02215, USA

5 Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 02215 USA

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BMC Genomics 2010, 11:342  doi:10.1186/1471-2164-11-342

Published: 28 May 2010

Additional files

Additional file 1:

Nucleotide sequence of primers used for RT-PCR to validate expression pattern of selected EC-restricted genes.

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Additional file 2:

Summary of miRNA Binding sites along with target and reference sequences.

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Additional file 3:

Immunohistochemistry based expression level of genes in different tissues. Rows represent the different tissues and columns represent the different EC-restricted genes. The expression level is shown in four color circle scheme i) Red represents strong expression ii) Orange represents moderate expression, iii) Yellow represents weak expression, iv) White represents no detectable expression and Black represents no representative images. The data was obtained from human protein atlas database.

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