Table 2

Differentially regulated genes regarding the cell cycle process after B[a]P exposure.

Symbol

Gene Name

Wt

Xpc^-/-

Bin3

bridging integrator 3

1.13

1.31

Brca2

breast cancer 2

-1.35

-1.34

Brms1

breast cancer metastasis-suppressor 1

-1.18

-1.34

Calr

calreticulin

-1.26

-1.31

Ccnb2

cyclin B2

-1.24

-1.16

Ccng2

cyclin G2

1.23

1.32

Ccnk

cyclin K

1.21

1.23

Cdc25c

cell division cycle 25 homolog C (S. cerevisiae)

-1.09

-1.30

Cdc27

cell division cycle 27 homolog (S. cerevisiae)

1.41

1.31

Cdc42

cell division cycle 42 homolog (S. cerevisiae)

1.34

1.50

Cdca1

cell division cycle associated 1

1.24

1.50

Cdca5

cell division cycle associated 5

1.18

1.30

Cdca8

cell division cycle associated 8

-1.24

-1.11

Cdk5rap3

CDK5 regulatory subunit associated protein 3

-1.24

-1.23

Cetn1

centrin 1

1.46

1.31

Cit

citron

1.20

1.35

Cks2

CDC28 protein kinase regulatory subunit 2

1.29

1.36

Cul3

cullin 3

1.28

1.18

Dhcr24

24-dehydrocholesterol reductase

1.50

1.43

Dnajc2

DnaJ (Hsp40) homolog, subfamily C, member 2

-1.42

-1.23

Fzr1

fizzy/cell division cycle 20 related 1 (Drosophila)

1.44

1.39

Gspt1

G1 to S phase transition 1

1.37

1.31

Hells

helicase, lymphoid specific

1.43

1.46

Incenp

inner centromere protein

1.17

1.29

Kif20a

kinesin family member 20A

1.54

1.41

Macf1

microtubule-actin crosslinking factor 1

1.16

1.49

Mad2l2

MAD2 mitotic arrest deficient-like 2 (yeast)

1.19

1.27

Mphosph6

M phase phosphoprotein 6

1.30

1.26

Mtus1

mitochondrial tumor suppressor 1

-1.22

-1.19

Nasp

nuclear autoantigenic sperm protein (histone-binding)

1.34

1.38

Nek4

NIMA (never in mitosis gene a)-related expressed kinase 4

1.31

1.37

Pin1

protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1

1.31

1.26

Ppp3ca

protein phosphatase 3, catalytic subunit, alpha isoform

-1.19

-1.22

Pten

phosphatase and tensin homolog

1.32

1.31

Rad17

RAD17 homolog (S. pombe)

1.22

1.27

Ranbp1

RAN binding protein 1

-1.24

-1.23

Rbm5

RNA binding motif protein 5

1.34

1.39

Sgol1

shugoshin-like 1 (S. pombe)

1.26

1.20

Smarcb1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

1.27

1.33

Sycp3

synaptonemal complex protein 3

1.34

1.30

Tacc3

transforming, acidic coiled-coil containing protein 3

1.31

1.34

Tipin

timeless interacting protein

-1.22

-1.24

Trrap

transformation/transcription domain-associated protein

-1.26

-1.22

Tubb6

tubulin, beta 6

-1.33

-1.44

Ube2i

ubiquitin-conjugating enzyme E2I

1.17

1.30

Zw10

ZW10 homolog (Drosophila), centromere/kinetochore protein

1.23

1.30

46 differentially regulated genes regarding the cell cycle process. Results are presented as average gene expression ratios between exposed and control samples.

Verhofstad et al. BMC Genomics 2010 11:333   doi:10.1186/1471-2164-11-333