Table 1

Comparison of gene expression ratios.

Pathway

Total # genes

Uw

Ux

Dw

Dx


Cell cycle

46

12

20

8

6

Chromatin structure

37

8

20

8

1

Translation

59

18

22

7

12

Spermatogenesis

32

10

12

9

1


Average gene expression ratios for genes involved in significantly regulated pathways are compared between Wt and Xpc-/- mice. The table shows the number of genes that are up or down regulated to a higher extent after B[a]P exposure in either genotype.

Uw, up regulated to a higher extent in Wt mice. Ux, up regulated to a higher extent in Xpc-/- mice. Dw, down regulated to a greater extent in Wt mice. Dx, down regulated to a greater extent in Xpc-/- mice.

Verhofstad et al. BMC Genomics 2010 11:333   doi:10.1186/1471-2164-11-333

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