Research article
Benzo(a)pyrene induces similar gene expression changes in testis of DNA repair proficient and deficient mice
1 Department of Health Risk Analysis and Toxicology, School for Nutrition, Toxicology and Metabolism, Maastricht University, PO box 616, 6200 MD Maastricht, the Netherlands
2 Laboratory for Health Protection Research, National Institute for Public Health and the Environment (RIVM), PO box 1, 3720 BA Bilthoven, the Netherlands
BMC Genomics 2010, 11:333 doi:10.1186/1471-2164-11-333
Published: 26 May 2010Additional files
Additional file 1:
Processes enriched among B[a]P induced genes. The data presented are terms enriched among the B[a]P induced gene list by DAVID/EASE with an FDR < 0.1.
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Additional file 2:
Processes enriched among B[a]P suppressed genes. The data presented are terms enriched among the B[a]P suppressed gene list by DAVID/EASE with an FDR < 0.1.
Format: XLS Size: 16KB Download file
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Additional file 3:
Processes affected by B[a]P exposure in mouse testis. The data presented are terms enriched among the B[a]P modulated gene list by DAVID/EASE with an FDR < 0.1.
Format: XLS Size: 26KB Download file
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Additional file 4:
Differentially regulated genes after B[a]P exposure involved in Chromatin structure. 37 differentially regulated genes involved in Chromatin structure. Results are presented as average gene expression ratios between exposed and control samples.
Format: XLS Size: 17KB Download file
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Additional file 5:
Differentially regulated genes after B[a]P exposure regulating Spermatogenesis. 32 differentially regulated genes involved in Spermatogenesis. Results are presented as average gene expression ratios between exposed and control samples.
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Additional file 6:
Differentially regulated genes after B[a]P exposure involved in Translation. 59 differentially regulated genes involved in Translation. Results are presented as average gene expression ratios between exposed and control samples.
Format: XLS Size: 20KB Download file
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Additional file 7:
Differentially regulated genes after B[a]P exposure involved in Mitochondrial function. 51 differentially regulated genes involved in mitochondrial function. Results are presented as average gene expression ratios between exposed and control samples. *genes involved in oxidative phosphorylation.
Format: XLS Size: 28KB Download file
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