Table 4

Top 20 liver-specific genes.

Entrez GeneID

Consolidated Rank

Rosetta1 MAX

Rosetta2 MAX

Stanford MAX

Genealtas MAX

Locuslink Symbol

Description


3263

1

5.25

4.90

5.02

3.48

HPX

Hemopexin, heme-binding plasma protein synthesized by the liver

3053

2

4.57

4.45

4.53

5.04

SERPIND1

Serpin peptidase inhibitor, clade D, member 1, cofactor of heparin in plasma

6580

3

6.38

5.69

4.16

2.75

SLC22A1

Solute carrier family 22 member 1, main organic cation uptake system in hepatocyte

462

4

4.86

3.47

3.33

3.75

SERPINC1

Serpin peptidase inhibitor, clade C (antithrombin), member 1

8608

5

5.13

2.72

4.30

4.45

RDH16

Retinol dehydrogenase 16, involved in lipid metabolism in liver

344

6

4.47

4.95

2.97

2.09

APOC2

Apolipoprotein C-II, component of very low density lipoprotein

1571

7

3.41

3.89

4.25

2.19

CYP2E1

Cytochrome P450, family 2, subfamily E, polypeptide 1. cytochrome oxidase system

6906

8

4.06

4.02

3.24

1.79

SERPINA7

Serpin peptidase inhibitor, clade A (antitrypsin), member 7

1559

9

3.24

3.35

2.93

2.69

CYP2C9

Cytochrome P450, family 2, subfamily 2, polypeptide 9 -

1551

10

3.57

3.45

2.46

2.51

CYP3A7

Cytochrome P450, family 3, subfamily A, polypeptide 7

732

11

5.54

3.25

1.52

4.17

C8B

Complement component 8, beta polypeptide

731

12

4.10

3.09

3.80

2.00

C8A

Complement component 8, alpha polypeptide

7448

13

5.10

3.46

1.30

4.79

VTN

Vitronectin - plasma protein promoting cell adhesion

350

14

2.67

3.43

2.84

2.27

APOH

Apolipoprotein H (beta-2-glycoprotein I)

1373

15

2.87

2.21

3.54

3.64

CPS1

CPS1 carbamoyl-phosphate synthetase 1, enzyme in the hepatic urea cycle

1361

16

2.97

2.78

2.55

2.52

CPB2

Carboxypeptidase B2 plasma protein regulating fibrinolyses,

3273

17

3.25

5.22

1.54

1.97

HRG

Histidine-rich glycoprotein, plasma protein

338

18

3.86

2.98

2.56

1.56

APOB

Apolipoprotein B, isoform apoB-100, exclusively synthesized in the liver

2168

19

4.83

2.81

2.50

1.51

FABP1

Fatty acid binding protein 1 found in the liver

10998

20

3.44

2.41

1.85

2.67

SLC27A5

Solute carrier family 27 (fatty acid transporter), member 5, involved in lipid synthesis


The top twenty genes based on the integrative MAX scoring are displayed.

Russ and Futschik BMC Genomics 2010 11:305   doi:10.1186/1471-2164-11-305

Open Data