Table 4 |
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|
Top 20 liver-specific genes. |
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|
Entrez GeneID |
Consolidated Rank |
Rosetta1 MAX |
Rosetta2 MAX |
Stanford MAX |
Genealtas MAX |
Locuslink Symbol |
Description |
|
|
|||||||
|
3263 |
1 |
5.25 |
4.90 |
5.02 |
3.48 |
HPX |
Hemopexin, heme-binding plasma protein synthesized by the liver |
|
3053 |
2 |
4.57 |
4.45 |
4.53 |
5.04 |
SERPIND1 |
Serpin peptidase inhibitor, clade D, member 1, cofactor of heparin in plasma |
|
6580 |
3 |
6.38 |
5.69 |
4.16 |
2.75 |
SLC22A1 |
Solute carrier family 22 member 1, main organic cation uptake system in hepatocyte |
|
462 |
4 |
4.86 |
3.47 |
3.33 |
3.75 |
SERPINC1 |
Serpin peptidase inhibitor, clade C (antithrombin), member 1 |
|
8608 |
5 |
5.13 |
2.72 |
4.30 |
4.45 |
RDH16 |
Retinol dehydrogenase 16, involved in lipid metabolism in liver |
|
344 |
6 |
4.47 |
4.95 |
2.97 |
2.09 |
APOC2 |
Apolipoprotein C-II, component of very low density lipoprotein |
|
1571 |
7 |
3.41 |
3.89 |
4.25 |
2.19 |
CYP2E1 |
Cytochrome P450, family 2, subfamily E, polypeptide 1. cytochrome oxidase system |
|
6906 |
8 |
4.06 |
4.02 |
3.24 |
1.79 |
SERPINA7 |
Serpin peptidase inhibitor, clade A (antitrypsin), member 7 |
|
1559 |
9 |
3.24 |
3.35 |
2.93 |
2.69 |
CYP2C9 |
Cytochrome P450, family 2, subfamily 2, polypeptide 9 - |
|
1551 |
10 |
3.57 |
3.45 |
2.46 |
2.51 |
CYP3A7 |
Cytochrome P450, family 3, subfamily A, polypeptide 7 |
|
732 |
11 |
5.54 |
3.25 |
1.52 |
4.17 |
C8B |
Complement component 8, beta polypeptide |
|
731 |
12 |
4.10 |
3.09 |
3.80 |
2.00 |
C8A |
Complement component 8, alpha polypeptide |
|
7448 |
13 |
5.10 |
3.46 |
1.30 |
4.79 |
VTN |
Vitronectin - plasma protein promoting cell adhesion |
|
350 |
14 |
2.67 |
3.43 |
2.84 |
2.27 |
APOH |
Apolipoprotein H (beta-2-glycoprotein I) |
|
1373 |
15 |
2.87 |
2.21 |
3.54 |
3.64 |
CPS1 |
CPS1 carbamoyl-phosphate synthetase 1, enzyme in the hepatic urea cycle |
|
1361 |
16 |
2.97 |
2.78 |
2.55 |
2.52 |
CPB2 |
Carboxypeptidase B2 plasma protein regulating fibrinolyses, |
|
3273 |
17 |
3.25 |
5.22 |
1.54 |
1.97 |
HRG |
Histidine-rich glycoprotein, plasma protein |
|
338 |
18 |
3.86 |
2.98 |
2.56 |
1.56 |
APOB |
Apolipoprotein B, isoform apoB-100, exclusively synthesized in the liver |
|
2168 |
19 |
4.83 |
2.81 |
2.50 |
1.51 |
FABP1 |
Fatty acid binding protein 1 found in the liver |
|
10998 |
20 |
3.44 |
2.41 |
1.85 |
2.67 |
SLC27A5 |
Solute carrier family 27 (fatty acid transporter), member 5, involved in lipid synthesis |
|
|
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|
The top twenty genes based on the integrative MAX scoring are displayed. |
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|
Russ and Futschik BMC Genomics 2010 11:305 doi:10.1186/1471-2164-11-305 |
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