Table 5

Comparison between cell lines--total of preferred classes

Factor

Cell line


GM128

K562

Other


GABP

0.991

0.976

NRSF

0.844

0.862

SRF

0.851

0.794

JunD

0.293

cFos

0.603

0.475

Max

0.675

SREBP1

0.742

STAT1

0.638

0.519

TR4

0.870

0.871

GATA1

0.736

NF-E2

0.536

TCF7L2

0.483

NFKB

0.686

YY1

0.876

ZNF263

0.856


Count

5

10

6

Average

0.733

0.755

0.661


Confidence Limit

0.477

0.674

0.503


This table gives a comparison between cell lines using a representative transcription factor for each family from Table 3. The last row gives the lower 95% confidence limit for the mean of the values in the column based on a one-sided t-test. The calculation includes the anomalously low value for JunD. We conclude that the choice of cell line does not affect the conclusion that TFBSs mainly occur in the preferred classes.

Evans BMC Genomics 2010 11:286   doi:10.1186/1471-2164-11-286

Open Data