Scenario for the multiplication of pseudogenes in Y. lipolytica. a) Rectangle represents the functional gene, dashed rectangles represent its corresponding pseudogenes. The tree topology is obtained by maximum likelihood reconstruction  based on the aligned nucleic acid sequences (branch lengths ignored). The emergence of frameshift mutations (!) and in-frame stop-codons (*) are indicated above corresponding branches. b) Alignment of the translation products of YALI0A14927g and its pseudogenes obtained by MUSCLE. frameshift mutations (!) and in-frame stop-codons (*) are boxed.
Lafontaine and Dujon BMC Genomics 2010 11:260 doi:10.1186/1471-2164-11-260