Additional file 11.
Effect of 1,25(OH)2D on c-Myc transcriptional activity at 6 h. Image representing effect of vitamin D induced supression of c-Myc on the mRNA level of c-myc target genes. Significantly differentially expressed transcripts at 6 h (SAM, FDR<5%) were analyzed by using Metacore Network analysis (Transcription factor). Up--regulated genes are marked with red circles; down--regulated with blue circles. Arrows are color coded to reflect the known regulatory action between two proteins. Red arrows between proteins indicates a negative regulatory effect, green arrows indicate a positive regulator effect, gray arrows indicate an unspecified regulatory effect.
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Kovalenko et al. BMC Genomics 2010 11:26 doi:10.1186/1471-2164-11-26