Strain-specific miRNA expression. A) Strain-differentially expressed miRNAs in the liver. The error bars indicate the estimated standard deviation (see methods for details). Only miRNAs of which the expression was significantly different (p < 0.05) are shown. The read frequency is normalized to the ocm (see methods for details). B) Differential expression of mir-34a confirmed by qPCR. The barplots show ΔCt values. This data was obtained from 3 × 3 replicates of each strain. The error bars show the combined standard deviation of all replicates for each miRNA. The student's T-test (2-sided) only assigned significance (p < 0.01) to mir-34a. NS, not significant.
Linsen et al. BMC Genomics 2010 11:249 doi:10.1186/1471-2164-11-249