Figure 5.

The optical mapping process. To generate a whole-genome optical map, DNA is sheared into fragments that are stretched and fixed onto an optical mapping surface and then digested using a restriction enzyme. The resulting pieces are optically analyzed and assembled into a genome-wide map.

Nagarajan et al. BMC Genomics 2010 11:242   doi:10.1186/1471-2164-11-242
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