Table 3

The expression of 26 genes in the very early stage of fulminant hepatitits mice model by real-time RT-PCR

genes

Number

ΔΔct (1 h/control)

ΔΔct (3 h/control)

ΔΔct (6 h/control)

ΔΔct (12 h/control)


ACSL1

12

1.58 ± 1.72

2.21 ± 3.81

0.47 ± 0.55#

0.71 ± 1.46


ALDH8A1

12

1.26 ± 0.62

5.16 ± 9.96

16.47 ± 40.57

2.78 ± 3.74


CMTM8

12

4.24 ± 5.47

60.46 ± 127.18

48.60 ± 111.88

62.93 ± 106.90


COLEC11

12

0.73 ± 0.29#

4.04 ± 2.35#*

3.27 ± 4.40

1.50 ± 2.00&


COLEC12

12

1.19 ± 0.54

3.86 ± 3.41#*

2.44 ± 2.77

6.59 ± 12.03


DPP4

12

0.87 ± 0.60

11.64 ± 6.76#*

14.91 ± 14.25#*

86.16 ± 218.29


FBXO3

12

1.79 ± 1.59

2.13 ± 1.91

1.64 ± 1.54

1.09 ± 0.72


FN3K

12

1.60 ± 1.98

3.38 ± 2.88#

2.01 ± 1.96

2.20 ± 3.57


GPD1L

12

2.61 ± 3.59

0.76 ± 0.83#

0.35 ± 0.30#

1.25 ± 3.02


HLF

12

1.49 ± 1.39

8.15 ± 10.11*#

4.26 ± 5.27

3.72 ± 5.31


KLB

12

1.01 ± 0.51

1.93 ± 1.11*#

2.93 ± 5.05

1.58 ± 1.91


MAP2K6

12

2.61 ± 1.75#

31.29 ± 90.44

0.94 ± 1.188*

1.40 ± 2.07


MPDZ

12

3.02 ± 2.23#

6.28 ± 4.92#

3.96 ± 5.98

5.11 ± 6.11


MTAP

12

1.77 ± 0.74#

11.75 ± 31.48

3.81 ± 8.55

1.56 ± 1.56


MSRB2

12

1.77 ± 1.60

7.07 ± 5.81#*

2.38 ± 2.35&

3.34 ± 3.52#


ORMDL1

12

1.15 ± 0.91

2.85 ± 1.81#*

1.57 ± 0.86&

1.23 ± 0.50&


POLG2

12

0.71 ± 0.51

5.74 ± 9.951

3.07 ± 3.28*

1.46 ± 0.84*


STARD5

12

1.39 ± 1.20

2.58 ± 5.52

2.09 ± 2.91

2.52 ± 1.03#*


PARD3

12

1.24 ± 1.50

6.74 ± 11.47

3.83 ± 4.79

2.05 ± 2.39


SLC29A1

12

0.82 ± 0.44

1.75 ± 1.35*

1.16 ± 1.71

0.33 ± 0.29#*&


SOX5

12

0.91 ± 0.65

1.56 ± 0.63#*

0.85 ± 0.52&

3.25 ± 3.84


TERT

12

0.82 ± 0.70

2.71 ± 2.52#*

1.89 ± 2.55

1.09 ± 2.22


CAR5A

12

1.87 ± 2.61

2.56 ± 3.16

0.54 ± 0.57#

0.45 ± 0.63#&


FASTKD1

12

0.38 ± 0.26#

1.75 ± 1.35*

0.95 ± 0.50*

0.46 ± 0.30#&◇


PDE7B

12

0.64 ± 0.40#

1.39 ± 2.18

0.44 ± 0.33#

0.59 ± 0.33#


FASTKD1

12

0.96 ± 0.96

1.90 ± 1.04#*

0.63 ± 0.44#&

0.60 ± 0.49#&


#: Compared with 0 h, the difference was significant (p < 0.05)

*: Compared with 1 h, the difference was significant (p < 0.05)

&: Compared with 3 h, the difference was significant (p < 0.05)

◇: Compared with 6 h, the difference was significant (p < 0.05)

Compared with normal controls, the expression of most of the 26 genes showed a statistical significant change (p < 0.05). Expressions of PARD3, ALDH8A1, CMTM8 and FBXO3 were also higher than those of normal controls, but there was no statistical significance (p > 0.05)

Chen et al. BMC Genomics 2010 11:240   doi:10.1186/1471-2164-11-240

Open Data