Table 1

Transcripts differentially expressed by at least two-fold in degenerative embryos as compared to blastocysts (FDR <= 0.15)

Gene symbol1

Gene name

Fold change

P value2


Upregulated

PHLDA2

pleckstrin homology-like domain, family A, member 2

8.18

0.00002

LOC540268

hypothetical LOC540268

4.19

0.00008

C14H8ORF70

chromosome 8 open reading frame 70 ortholog

3.01

0.00017

Downregulated

CMBL

carboxymethylenebutenolidase homolog (Pseudomonas)

2.16

0.00004

CTNS

cystinosis, nephropathic

2.09

0.00005

TNNC2

troponin C type 2 (fast)

3.47

0.00015

TGFBR3

transforming growth factor, beta receptor III

2.22

0.00022

DAPP1

dual adaptor of phosphotyrosine and 3-phosphoinositides

3.01

0.00024

FERMT2

fermitin family homolog 2 (Drosophila)

2.07

0.00026

PECR

peroxisomal trans-2-enoyl-CoA reductase

2.14

0.00031

SLC11A23

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

2.33

0.00035

Bt.19510.2.A1_at

transcribed locus

2.33

0.00036

Bt.21611.1.S1_at

transcribed locus

2.32

0.00037

SHISA2

shisa homolog 2 (Xenopus laevis)

2.54

0.00039

Bt.22693.1.A1_at

transcribed locus

7.31

0.00042

MGC157372

hypothetical LOC614796

2.34

0.00046

MCF2L

MCF.2 cell line derived transforming sequence-like

4.32

0.00050

SLC10A1

solute carrier family 10 (sodium/bile acid cotransporter family), member 1

12.67

0.00055

SERPINC1

serpin peptidase inhibitor, clade C (antithrombin), member 1

2.23

0.00058

CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

2.14

0.00063

Bt.6523.1.A1_at

transcribed locus

2.49

0.00077

LOC521943

similar to hCG1788238

3.41

0.00078

SLC11A23

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

2.19

0.00079

Bt.17542.1.S1_at

transcribed locus

2.43

0.00081

Bt.27347.1.A1_at

transcribed locus

3.05

0.00082

PTPRK

protein tyrosine phosphatase, receptor type, K

4.04

0.00087

Bt.19644.1.A1_at

transcribed locus

3.20

0.00088

FDFT1

farnesyl-diphosphate farnesyltransferase 1

2.52

0.00089

CYP51

cytochrome P450, family 51, subfamily A, polypeptide 1

3.48

0.00094

RP2

retinitis pigmentosa 2 (X-linked recessive)

4.41

0.00095

LOC790609

similar to aminoacylase 1

2.45

0.00098

LOC513587

similar to UPF0474 protein C5orf41

4.33

0.00116

SLC25A21

solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21

2.75

0.00119


1 Transcripts without annotations were identified by probe set ID.

2 Raw p values from significance analysis of microarray (SAM), transcripts were ordered according to their p values.

3 The gene SLC11A2 is represented by multiple probe sets on the Bovine Genome Array

Huang et al. BMC Genomics 2010 11:23   doi:10.1186/1471-2164-11-23

Open Data