Comparisons of down and up-regulated transcripts. Venn Diagram illustrating fold gene expression differences between 2m, 8m, and 26m (t-test <2-fold, p<0.01) of 40,359 transcripts. Expression levels of 2111 transcripts decreased from 2m to 8m and 2547 transcripts decreased from 8m to 26m. Only 86 transcripts commonly decreased over both age groups. Analysis of up-regulated genes in the same manner revealed 1487 transcripts that were increased from 2m to 8m and 2402 increased from 8m to 26m. There was no overlap.
Wilson et al. BMC Genomics 2010 11:229 doi:10.1186/1471-2164-11-229