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Open Access Research article

Differential transcript expression between the microfilariae of the filarial nematodes, Brugia malayi and B. pahangi

Michael M Kariuki1, Leonard B Hearne2 and Brenda T Beerntsen1*

Author Affiliations

1 Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA

2 Department of Statistics, College of Arts and Science, University of Missouri, Columbia, MO 65211, USA

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BMC Genomics 2010, 11:225  doi:10.1186/1471-2164-11-225

Published: 7 April 2010

Additional files

Additional file 1:

Brugia gene transcripts that are up-regulated in B. pahangi microfilariae. This file contains a list of genes represented by probes on the microarray that had signal intensity ratios of 2 or higher in B. pahangi microfilariae and a FDR estimate of 5%. These genes were considered preferentially expressed and manually mapped into the appropriate KEGG pathway. a Genes represented by more than one probe on the BmV2 array. For these genes, an average of the p-value and signal intensity ratio is shown. Genes in each of the KEGG pathway groups are ranked according to their ratios.

Format: DOC Size: 124KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 2:

Brugia gene transcripts that are up-regulated in B. malayi microfilariae. This file contains a list of genes represented by probes on the microarray that had signal intensity ratios of 2 or higher in B. malayi microfilariae and a FDR estimate of 5%. These genes were considered preferentially expressed and manually mapped into the appropriate KEGG pathway. a Genes represented by more than one probe on the BmV2 array. For these genes, an average of the p-value and signal intensity ratio is shown. Genes in each of the KEGG pathway groups are ranked according to their ratios.

Format: DOC Size: 113KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data