Table 1

ZNF genes and transcriptsa in the human 8q24.3 ZNF cluster on contig AF235103 (chr 8:145.893.231 -- 146.238.749)

Gene name (HUGO)

Locationb

Strand

Nucleotide sequencec

RefSeqd

Gene IDe

ENSEMBL transcript ID.f

No of exons

cDNA (bp)

Amino acids (aa)

Remarks


ZNF251

145 917 103

--

145 951 786

(34 684 bp)

-

AK000435

AK091638

XM_291262

BC006258

NM_138367

90987

ENST00000

292562

5

3018

671

KRAB-A

KRAB-B


ZNF34

145 968 415

--

145 983 530

(15 116 bp)

-

AK096508

AL833814

BC028136

BC004480

NM_030580

80778

ENST00000

343459

6

2830

539

KRAB-A

KRAB-B

alias Kox32


ZNF517

145 995 065

--

146 006 265

(11 201 bp)

+

AK097278

AK096527

AK131440

XM_291261

AX721108

NM_213605

340385

ENST00000

359971

6

>2536

>527

KRAB-A

KRAB-B


ZNF7

146 023 815

--

146 039 409

(15 595 bp)

+

M29580

AK096025

NM_003416

7553

ENST00000

325241

5

2345

686

KRAB-A

KRAB-B

alias: Kox4


ZNF250

146 077 336

--

146 097 650

(20 315 bp)

-

AK054888

BC017091

AK095705

X16282

NM_021061

NM_001103159

58500

ENST00000

292579

6

2168

560

KRAB-A

KRAB-B

alias:

ZNF647


ZNF 16

146 126 577

--

146 147 078

(20 502 bp)

-

BC010996

AK096815

AF244088

X52340

AL834451

NM_006958

NM_001029976

7564

ENST00000

276816

4

>2501

>715

no KRAB

alias:

Kox9


ZNF252

146 169 773

--

146 191 428

(21 656 bp)

146 169 773

--

146 199 082

(29 310 bp)

-

BC016287

BC019922

AK128723

BC065734

NR_023392

286101

ENST00000

355436

2

5

5731

5428

461

461

KRAB-A not in ZNF ORF;

KRAB-B with stop codon after stop in frame more zinc fingers


a Description of the largest transcript of the respective gene model

b Chromosomal position according to human genome build hg18 (UCSC browser at http://genome.ucsc.edu webcite; derived from NCBI genome assembly 36.1)

c Selected NCBI GenBank and

d Reference sequence collection accession numbers of representative cDNA/EST sequences

e Entrez GeneID

f Transcript proposed at http://www.ensembl.org webcite

Lorenz et al. BMC Genomics 2010 11:206   doi:10.1186/1471-2164-11-206

Open Data