GSEA analysis of human and mouse expression datasets and ontological categories of LEA gene lists. Up- and down-regulated statistically significant GSEA gene sets were subjected to LEA analysis and resulting genes were grouped in related ontological categories. The pie chart diagrams of up- and down-regulated LEA genes are shown on the left and on the right, respectively. The same ontological categories are represented by the same color on the pie charts. Only the first six most abundant ontological categories are shown for each set. To save space, the following ontological categories were shortened as follows: Translation -Translation/Protein biosynthesis/Ribosome biogenesis; Transcription - Transcription/RNA processing; DNA repair - DNA repair/replication/recombination; Cell cycle - Cell cycle/Mitosis/Cytokinesis; Immune response - Immune/Defense/Antiviral/Inflammatory response.
Pemov et al. BMC Genomics 2010 11:194 doi:10.1186/1471-2164-11-194